Volume 1, Issue 1, June 2013, Page: 32-36
The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats
Areshidze David, Center of Cell Biology and Applied Biotechnology, Moscow State Regional University, Moscow, Russian federation
Timchenko Luydmila, Institute of the living systems of the North Caucasus Federal University, Stavropol, Russian federation
Кozlova Maria, Center of Cell Biology and Applied Biotechnology, Moscow State Regional University, Moscow, Russian federation
Received: May 26, 2013;       Published: Jul. 30, 2013
DOI: 10.11648/j.ajbls.20130101.16      View  2254      Downloads  93
Abstract
Investigation of the influence of the enzymatic hydrolyzate of Chlorophytum comosumthe first on the liver of rats at its toxic damage showed that the substrate has expressed a pronounced hepatoprotective effect. Under its influence in the rat liver morphological changes induced by CCl4 are much less pronounced than in the controls. There are also less significant deviations from normal levels of ALT, AST and bilirubin. Information analysis of the state of the organ indicates that the level of adaptation and regeneration opportunities of the liver of rats treated with an enzymatic hydrolyzate of Chlorophytum comosum is significantly higher than that of the liver of rats with experimental toxic liver damage without the use of tested substrate.
Keywords
Liver, Hydrolizate, Hepatocyte, Chlorophytum Comosum
To cite this article
Areshidze David, Timchenko Luydmila, Кozlova Maria, The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats, American Journal of Biomedical and Life Sciences. Vol. 1, No. 1, 2013, pp. 32-36. doi: 10.11648/j.ajbls.20130101.16
Reference
[1]
T.H.Arnoldand B.C. de Wet,"Plants of southern Africa: names and distribution", Memoirs of the Botanical Surveys of South Africa, 1993, vol. 62, pp.968.
[2]
S.E. Afton, B. Catron and J.A. Caruso,"Elucidating the selenium and arsenic metabolic pathways following exposure to the non-hyperaccumulatingChlorophytum comosum, spider plant", Journal of Experimental Botany 2009, vol. 60; 4, pp.1289-1297.
[3]
G.G.Avtandilov 2008.Medical Morphometry [in Russian]. Moscow:Meditsina,. pp.298.
[4]
M. Giese, U. Bauer-Doranth, S.Langebartels, and H. Sandermann" Detoxification of Formaldehyde by the Spider Plant (Chlorophytum comosum L.) and by Soybean (Glycine max L.) Cell-Suspension Cultures", Plant Physiology1994, vol. 4, pp. 1301-1309.
[5]
A.J.Haagen-Smit, E.F. Darley, M.Zaitlin, H. Hull and W.Noble "Investigation on injury to plants from air pollution in the Los Angeles area", Plant Physiology, 1952; vol. 27, pp. 18-34.
[6]
C.P. Kala, B.S.Dhyani and B.S.Sajwan. "Developing the medicinal plants sector in northern India: challenges and opportunities", Journal of Ethnobiology and Ethnomedicine. 2006,vol. 6, pp. 32-38.
[7]
M.D. Logsdon, Jr. Meyn,and P.C.Besa. "Apoptosis and the Bcl–2 gene family: patterns of expression and prognostic value in stage I and II follicular center lymphoma?",Int J RadiatOncolBiolPhys 1999,vol.44, pp. 19-29.
[8]
H. Matsushita, H.Kuwabara, H. Matsushita, S. Ishikawa and M. Mochizuki. "Apoptosis Induced in Human Cell Lines by a Butanol Extract from Chlorophytum comosum", Roots Journal of Health Science, 2005,vol. 51, pp. 341-345.
[9]
M. Thakur, S. Bhangava and V. Dixit "Immunomodulatory Activity of Chlorophytum borivilianum", Sant. Evid Based Complement Alternative Medicine, 2007, vol. 4, pp. 419-423.
[10]
R.A. Wood, R. Orwell, M.D. Burchett, J. Tarran and S.K. Brown. "Absorption of organic compounds in indoor air by commonly used indoor plants", Proceedings of Healthy Buildings,2000, vol. 2, pp. 125-130.
Browse journals by subject