Volume 7, Issue 4, August 2019, Page: 79-83
Interest of the D-dimers Assay in the Medical Care of Thromboembolic Disease: Experience of the Hematology Laboratory of the Military Hospital Avicenne of Marrakech
Maryam Mouamin, Laboratory Department of Hematology, Avicenna Hospital/Faculty of Medecine and Pharmacy of Marrakech, Marrakech, Morocco
Asmaa Allali, Laboratory Department of Hematology, Avicenna Hospital/Faculty of Medecine and Pharmacy of Marrakech, Marrakech, Morocco
Ghali Boufrioua, Laboratory Department of Hematology, Avicenna Hospital/Faculty of Medecine and Pharmacy of Marrakech, Marrakech, Morocco
Jihane Belkhair, Laboratory Department of Hematology, Avicenna Hospital/Faculty of Medecine and Pharmacy of Marrakech, Marrakech, Morocco
Hicham Yahyaoui, Laboratory Department of Hematology, Avicenna Hospital/Faculty of Medecine and Pharmacy of Marrakech, Marrakech, Morocco
Mustapha Ait Amer, Laboratory Department of Hematology, Avicenna Hospital/Faculty of Medecine and Pharmacy of Marrakech, Marrakech, Morocco
Mohamed Chakour, Laboratory Department of Hematology, Avicenna Hospital/Faculty of Medecine and Pharmacy of Marrakech, Marrakech, Morocco
Received: Jun. 22, 2019;       Accepted: Jul. 23, 2019;       Published: Aug. 10, 2019
DOI: 10.11648/j.ajbls.20190704.12      View  91      Downloads  15
Abstract
The objective of our study is to show the benefits of D-dimers (DD) dosing in the diagnostic care of thromboembolic disease. A retrospective study conducted over a 2-year period (2016-2017), including all DD dosing requests sent to the hematology laboratory at the Avicenne Military Hospital, excluding patients under 18 years of age. The quantitative assay was performed by an immunoturbidimetric method on STA Compact automaton, (STAGO), with STA®-Liatest® D-Di reagents with respect for the pre-analytical phase. We collected 100 samples over the study’s two year period. The requests mainly came from the emergencies and polyvalent intensive care unit. The clinical picture suggested a deep vein thrombosis in 56% of cases and pulmonary embolism in 44% of cases. The search was positive in 78% of cases. Sensitivity and negative predictive value were 100%. Specificity in the ambulatory population was 66.66% vs 28% in the hospital population and also decreased with age.
Keywords
D-dimeres, Veinous Thromboembolic Disease, Age Factor, Inpatient and Outpatient
To cite this article
Maryam Mouamin, Asmaa Allali, Ghali Boufrioua, Jihane Belkhair, Hicham Yahyaoui, Mustapha Ait Amer, Mohamed Chakour, Interest of the D-dimers Assay in the Medical Care of Thromboembolic Disease: Experience of the Hematology Laboratory of the Military Hospital Avicenne of Marrakech, American Journal of Biomedical and Life Sciences. Vol. 7, No. 4, 2019, pp. 79-83. doi: 10.11648/j.ajbls.20190704.12
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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