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Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana

Received: 29 August 2023    Accepted: 13 September 2023    Published: 27 September 2023
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Abstract

Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.

Published in American Journal of Biomedical and Life Sciences (Volume 11, Issue 5)
DOI 10.11648/j.ajbls.20231105.12
Page(s) 92-100
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Persea Americana, Seed, Phytochemical Composition, Antioxidant and Antiradical Activities

References
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    Kwami Lumo Awaga, Kosi Mawuéna Novidzro, Bognam Kpensaga, Koffi Apeti Gbogbo, Et Kossi Honoré Koumaglo. (2023). Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. American Journal of Biomedical and Life Sciences, 11(5), 92-100. https://doi.org/10.11648/j.ajbls.20231105.12

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    Kwami Lumo Awaga; Kosi Mawuéna Novidzro; Bognam Kpensaga; Koffi Apeti Gbogbo; Et Kossi Honoré Koumaglo. Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. Am. J. Biomed. Life Sci. 2023, 11(5), 92-100. doi: 10.11648/j.ajbls.20231105.12

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    Kwami Lumo Awaga, Kosi Mawuéna Novidzro, Bognam Kpensaga, Koffi Apeti Gbogbo, Et Kossi Honoré Koumaglo. Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. Am J Biomed Life Sci. 2023;11(5):92-100. doi: 10.11648/j.ajbls.20231105.12

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  • @article{10.11648/j.ajbls.20231105.12,
      author = {Kwami Lumo Awaga and Kosi Mawuéna Novidzro and Bognam Kpensaga and Koffi Apeti Gbogbo and Et Kossi Honoré Koumaglo},
      title = {Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {11},
      number = {5},
      pages = {92-100},
      doi = {10.11648/j.ajbls.20231105.12},
      url = {https://doi.org/10.11648/j.ajbls.20231105.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20231105.12},
      abstract = {Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana
    AU  - Kwami Lumo Awaga
    AU  - Kosi Mawuéna Novidzro
    AU  - Bognam Kpensaga
    AU  - Koffi Apeti Gbogbo
    AU  - Et Kossi Honoré Koumaglo
    Y1  - 2023/09/27
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ajbls.20231105.12
    DO  - 10.11648/j.ajbls.20231105.12
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 92
    EP  - 100
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20231105.12
    AB  - Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.
    VL  - 11
    IS  - 5
    ER  - 

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Author Information
  • Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo; Département de Biochimie, Faculty des Sciences, University de Lomé, Lomé, Togo

  • Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo; Departement de Chimie, Faculty des Sciences, University de Lomé, Lomé, Togo

  • Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo; Departement de Chimie, Faculty des Sciences, University de Lomé, Lomé, Togo

  • Laboratoire de Biologie et l’Ecologie Végétale (LBEV), University de Lomé, Lomé, Togo; Departement de Botanique, Faculty des Sciences, University de Lomé, Lomé, Togo

  • Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo

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