American Journal of Biomedical and Life Sciences

Volume 1, Issue 4, December 2013

  • A Study of Airborne Fungal Spores of Anyigba, Kogi State, Nigeria

    Essien, Benjamin Christopher, Taiga, Akpovughaye, Suleiman, Mohammed Nasirudeen, Idachaba, Stehen Onojo, Aniama, Salome Ojone, Edegbo, Emmanuel

    Issue: Volume 1, Issue 4, December 2013
    Pages: 70-74
    Received: 29 October 2013
    Published: 30 November 2013
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    Abstract: Airborne fungal spores of Anyigba, Dekina Local Government Area, Kogi State, Nigeria during the months of March – December, 2012 were trapped,acetolysed and analysedpalynologically to determine the genera of airborne fungal spores and/or particles present in the atmosphere. A total of 9491 fungal spores were counted. The predominant spore types inc... Show More
  • Hepatoprotective Effect of Parkia Biglobosa Stem Bark Methanolic Extract on Paracetamol Induced Liver Damage in Wistar Rats

    Meraiyebu Ajibola, Olaniyan Olugbemi, Abutu Stephanie, Dare Joseph, Atsukwei Denen

    Issue: Volume 1, Issue 4, December 2013
    Pages: 75-78
    Received: 5 October 2013
    Published: 10 December 2013
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    Abstract: This study was designed to investigate the effect of the methanolic extract of parkia biglobosa stem bark on a single daily dose of oral administration of 500 mg/kg BW of paracetamol (acetaminophen, PCM) induced hepatotoxicity in wistar rats. The rats were divided into (5 groups. The rats in group I served as control and received distilled water, g... Show More
  • A Review of the Occurrence of Non-Alkaloid Constituents in Uncaria Species and Their Structure-Activity Relationships

    Ndagijimana Andre, Xiaoming Wang, Yongzhi He, Guixiang Pan, Agyemang Kojo, Ying Liu

    Issue: Volume 1, Issue 4, December 2013
    Pages: 79-98
    Received: 19 November 2013
    Published: 20 December 2013
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    Abstract: A good understanding of a medicinal plant is based on fundamental knowledge of its chemical constituents and their pharmacological effects. The non-alkaloids constituents isolated from Uncaria species have been increasingly investigated recently. The anti-inflammatory, anti-oxidant and anti-cancer properties have been studied in many non-alkaloids ... Show More
  • Plasma Membrane-Derived Vesicles in Sickle Cell Disease: A Possible Indicator of the Continuous Endothelial Stimulation and/or Injury to Blood Cells

    Samuel Antwi-Baffour, Abena Nyarkoah Wiredu, Ransford Kyeremeh, Seidu Abdulai Mahmood

    Issue: Volume 1, Issue 4, December 2013
    Pages: 99-102
    Received: 19 December 2013
    Published: 30 December 2013
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    Abstract: Plasma membrane-derived vesicles (PMVs) are released into circulation in response to normal and stress/pathogenic conditions. They are of tremendous significance for the prediction, diagnosis, and observation of the therapeutic success of many diseases. Knowledge of their functional properties would contribute to a better understanding of the patho... Show More
  • Association between Haptoglobin Genotype Polymorphism and Type Two (2) Diabetes in Accra, Ghana

    Charles Brown, Benedicta Awisi, Harry Asmah, Batholomew Dzudzor, Anita Ghansah

    Issue: Volume 1, Issue 4, December 2013
    Pages: 103-109
    Received: 1 December 2013
    Published: 20 January 2014
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    Abstract: Polymorphism of the haptoglobin (Hp) gene, characterized by alleles Hp1 and Hp2, gives rise to structurally and functionally distinct Hp protein phenotypes: Hp1-1, Hp2-1, and Hp2-2. The corresponding proteins have structural and functional differences that have influence on a particular disease. For example, Hp genotype is an independent risk facto... Show More